Thymosin Alpha-1 peptide is a naturally
occurring 28 amino acid peptide derived from
the N-terminal region of prothymosin alpha.
Originally isolated from thymic tissue,
Thymosin Alpha-1 peptide is one of the most
extensively studied immune modulating peptides
in research settings worldwide. With over four
decades of published research, Thymosin Alpha-1
peptide has one of the longest and most
thoroughly documented research profiles of
any synthetic peptide available for laboratory use.
TECHNICAL SPECIFICATIONS
Molecular Formula: C129H215N33O55
Molecular Weight: 3108.29 g/mol
Purity: ≥99% by HPLC
Appearance: White lyophilised powder
Storage: Store at -20°C
CAS Number: 62304-98-7
Sequence: Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-
Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-
Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-
Asn-OH (28 amino acids)
ABOUT THYMOSIN ALPHA-1 PEPTIDE RESEARCH
Thymosin Alpha-1 peptide has been extensively
studied in immunology and immune modulation
research environments worldwide. As a thymic
peptide, Thymosin Alpha-1 interacts with
Toll-like receptor signalling pathways and
dendritic cell activation in research models
making it one of the most relevant compounds
for studying innate and adaptive immune
responses in controlled laboratory settings.
Research involving Thymosin Alpha-1 peptide
has been published across thousands of peer
reviewed journals covering immunology, virology
and cellular biology. The compound has one
of the longest research histories of any
synthetic peptide available for laboratory
research.
The mechanism of action of Thymosin Alpha-1
peptide in research models involves interaction
with multiple components of the immune system.
Studies have documented Thymosin Alpha-1
peptides effects on dendritic cell maturation,
T-lymphocyte differentiation, natural killer
cell activity and cytokine production in
controlled laboratory environments. This broad
spectrum of immune modulatory activity makes
Thymosin Alpha-1 peptide valuable for studying
both innate and adaptive immunity.
Thymosin Alpha-1 peptide was first isolated
by Goldstein and colleagues in the 1970s from
thymic extracts. The subsequent determination
of its sequence and synthesis of the pure
peptide opened a new era in thymic peptide
research. Decades of subsequent research have
characterised Thymosin Alpha-1 peptides
interactions with multiple immune cell
populations and identified numerous molecular
targets for its immunomodulatory activity.
IMMUNOLOGICAL RESEARCH APPLICATIONS
Thymosin Alpha-1 peptide is relevant to
multiple areas of immunological research.
In innate immunity research, studies have
examined its effects on pattern recognition
receptor signalling, particularly Toll-like
receptor pathways. In adaptive immunity
research, Thymosin Alpha-1 peptide has been
studied for its effects on T-cell
differentiation, regulatory T-cell function
and antibody production. The compound is also
used in virology research examining host
immune responses to viral infection models.
PURITY AND QUALITY ASSURANCE
Every batch of Thymosin Alpha-1 peptide
supplied by PeptideCores undergoes rigorous
independent third-party testing. HPLC testing
confirms purity at 99% or above. Mass
spectrometry confirms the full 28-amino acid
sequence integrity. Full Certificate of
Analysis issued for every batch dispatched.
STORAGE AND HANDLING
Store Thymosin Alpha-1 peptide at minus 20
degrees Celsius away from direct light and
moisture. Stable for up to 24 months. Once
reconstituted store at 4 degrees Celsius
and use within appropriate research timelines.
WHY CHOOSE PEPTIDECORES FOR THYMOSIN ALPHA-1
PeptideCores supplies Thymosin Alpha-1
exclusively for laboratory and research purposes.
Each order includes a Certificate of Analysis
confirming the full 28-amino acid sequence
purity and composition. Worldwide discreet
shipping on every order.
ORDERING AND SHIPPING
Thymosin Alpha-1 peptide orders are processed
within 24 hours of payment confirmation.
Worldwide discreet shipping with full tracking.
No reference to contents on outer packaging.
FREQUENTLY ASKED QUESTIONS
What is the purity of your Thymosin Alpha-1?
Our Thymosin Alpha-1 is HPLC verified
at 99% plus purity with a full Certificate
of Analysis confirming the complete 28-amino
acid sequence included with every order.
What immune cell types does Thymosin Alpha-1
affect in research?
Research has documented effects on dendritic
cells, T-lymphocytes, natural killer cells
and macrophages in laboratory models making
it valuable for comprehensive immunological
research.
How long has Thymosin Alpha-1 been studied?
Thymosin Alpha-1 peptide has been studied
since the 1970s following its isolation from
thymic tissue. It has one of the longest
research histories of any synthetic peptide
available for laboratory research today.
How should Thymosin Alpha-1 peptide be stored?
Store lyophilised Thymosin Alpha-1
at minus 20 degrees Celsius away from direct
light and moisture. Stable for up to 24 months.
DISCLAIMER
This product is intended for laboratory research
purposes only. It is not intended for human or
veterinary use, diagnosis, treatment or prevention
of any condition or disease. Only qualified
researchers should handle this compound in
appropriate laboratory settings.



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